人才队伍
郭金山 研究员

学历:博士研究生

学科:高分子化学与物理

电话:

邮箱:guojinshan@ciac.ac.cn

地址:吉林省长春市人民大街5625号

邮编:130022

简历介绍

    198211月生于河南周口。中国科学院长春应用化学研究所研究员、博士生导师,中国科学院人才计划、“广东特支计划”青年拔尖人才获得者。20057月毕业于山东大学,获学士学位;20111月毕业于中国科学院长春应用化学研究所,获博士学位。毕业后赴美,先后在德州大学阿灵顿分校、宾夕法尼亚州立大学和哈佛大学从事研究,2016-2017年有一年美国医疗器械公司工作经历。20196月以“高层次引进人才”入职南方医科大学,任教授、博导;20243月回所工作。长期从事生物医用高分子合成、生物材料和再生医学研究,率先开发了系列具有骨代谢调节功能的高强韧柠檬酸基骨仿生材料和医用胶粘剂,在国际上处于领先地位。在Advanced MaterialsAdvanced Functional Materials等杂志发表SCI论文60余篇,英文专著2章;拥有中、美、PCT专利20余项(转让3项),基于专利技术成功研制出3FDA批准的柠檬酸基界面骨螺钉和1FDA批准的体表医用胶;先后主持和参与国家自然科学基金和广东省基金委、卫健委纵向项目6项(包括区域联合重点和面上)以及卡姿兰和谷雨委托研发项目10余项。荣获广东省科技进步一等奖、华夏医学科技三等奖和2015年宾夕法尼亚州立大学创新奖等多项奖励。应邀担任Frontiers in Bioengineering and Biotechnology副主编、Bioactive Materials特刊主编及Nature Communications等杂志评审专家。

代表性成果

代表论文:

1.Jinshan Guo,Zhiwei Xie,Richard T Tran,Denghui Xie,Dadi Jin,Xiaochun Bai,Jian Yang*. Click chemistry plays a dual role in biodegradable polymer design. Advanced Materials,2014,26,1906-1911.

2.Jinshan Guo#,Xinggui Tian#,Denghui Xie#,Kevin Rahn,Ethan Gerhard,Michelle Laurel Kuzma,Dongfang Zhou,Cheng Dong,Xiaochun Bai*,Zhihui Lu*,Jian Yang*. Citrate-based tannin-bridged bone composites for lumbar fusion. Advanced Functional Materials 2020,30,2002438.2020年度中国骨科领域高价值国际论文)

3.Keke Wu,Meimei Fu,Yitao Zhao,Ethan Gerhard,Yueli,Jian Yang,Jinshan Guo*. Anti-oxidant anti-inflammatory and antibacterial tannin-crosslinked citrate-based mussel-inspired bioadhesives faciliate scarless wound healing. Bioactive Materials 2023,20,93-110. (高被引文章)

4.Meimei Fu#,Yitao Zhao#,Yue Wang,Yue Li,Min Wu,Qi Liu,Zhiguo Hou,Zhihui Lu,Keke Wu*,Jinshan Guo*. On-demand removable self-healing and pH-responsive europium-releasing adhesive dressing enables inflammatory microenvironment modulation and angiogenesis for diabetic wound healing. Small 2023,19,2205489.

5.Yue Li#,Yong Miao#,Lunan Yang#,Gaofeng Wang,Meimei Fu,Yue Wang,Danlan Fu,Junfei Huang,Jin Wang,Zhexiang Fan,Zhihui Lu*,Jinshan Guo*,Zhiqi Hu*. Malate-based polyester chemically shielded metal-phenolic networks coated artificial hair fibers with long-lasting antimicrobial and anti-inflammatory performance. Chemical Engineering Journal 2023,455,140572.

6.Yue Wang#,Yitao Zhao#,Shiyuan Ma,Meimei Fu,Min Wu,Jintao Li,Keke Wu,Xiuli Zhuang*,Zhihui Lu*,Jinshan Guo*. Injective programmable proanthocyanidin-coordinated zinc-based composite hydrogel for infected bone repair. Advanced Healthcare Materials 2024,13(6),2302690.

7.Yitao Zhao#,Jintao Li#,Lingli Liu#,Yue Wang,Yan Ju,Chun Zeng*,Zhihui Lu*,Denghui Xie*,Jinshan Guo*. Zinc-based tannin-modified composite microparticulate scaffolds with balanced antimicrobial activity and osteogenesis for infected bone defect repair. Advanced Healthcare Materials 2023,12(20),2300303.

8.Min Wu,Yitao Zhao,Meihan Tao,Meimei Fu,Yue Wang,Qi Liu,Zhihui Lu,Jinshan Guo*. Malate-based biodegradable scaffolds activate cellular energetic metabolism for accelerated wound healing. ACS Applied Materials & Interfaces 2023,15(44),50836–50853.

9.Yue Li,Yong Miao,Lunan Yang,Yitao Zhao,Keke Wu,Zhihui Lu,Zhiqi Hu*,Jinshan Guo*. Recent advances in the development and antimicrobial applications of metal-phenolic networks. Advanced Science 2022,9,2202684.

10.Jinshan Guo#,Gloria B. Kim#,Dingying Shan,Jimin P. Kim,Jianqing Hu,Wei Wang,Fawzi G. Hamad,Guoying Qian,Elias B. Rizk,Jian Yang*. Click chemistry improved wet adhesion strength of mussel-inspired citrate-based antimicrobial bioadhesives. Biomaterials 2017,112,275-286.

代表专利:

1.发明专利:具有预防疤痕生成功能的可降解抗氧化胶黏剂及其制备方法和应用

  专利号:CN202210410982.6

  发明人:郭金山,吴可可

  授权公告日:2022-07-01

2.发明专利:一种复合胶黏剂及其制备方法和应用

  专利号:CN202110744192.7

  发明人:郭金山,赵益涛

授权公告日:2022-08-16

3.发明专利:一种配位化合物及其制备方法和应用

  专利号:CN202110956537.5

  发明人:郭金山,吴可可 授权公告日:2023-10-03

4.发明专利:生物功能型单组分医用胶粘剂及其制备方法、应用

  专利号:CN202210450771.5  

  发明人:卢智慧,侯志国,郭金山  

  授权公告日:2023-07-25

5.发明专利:促组织再生型双组分医用胶粘剂及其制备方法、应用  

  专利号:CN202210450770.0  

  发明人:卢智慧,侯志国,郭金山  

  授权公告日:2024-01-02

代表著作:

重大成果: