人才队伍
姜秀娥 研究员;杰青;优青

学历:博士研究生

学科:分析化学

电话:0431-85262069

邮箱:jiangxiue@ciac.ac.cn

地址:吉林省长春市人民大街5625号

邮编:130022

简历介绍

  1976年2月生于辽宁抚顺。中国科学院长春应用化学研究所研究员、博士生导师。2005年博士毕业于中国科学院长春应化所。2006年~2010年先后在德国Bielefeld大学、德国ULM大学及德国Karlsruhe技术研究所从事洪堡学者及博士后研究。2010年加入中国科学院长春应化所电分析化学国家重点实验室,组建独立科研团队。2013年获“国家优秀青年科学基金”资助。长期从事生物界面的谱学电化学分析方面的工作,系统揭示了水分子在生物膜界面对非共价相互作用的指示、调节功能及纳米材料的动态变化与细胞响应的构效关系。以第一及通讯作者等身份在Proc. Natl. Acad. Sci. USA, J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Nano, Adv. Funct. Mater., Anal. Chem.等SCI学术期刊发表文章80余篇,SCI他引3700余次。授权发明专利4项。应邀为Springer出版社撰写英文学术专著2章。作为课题负责人先后承担了国家自然科学基金5项(包括优青、国际合作和面上),省部级项目7项。曾获中国科学院宝洁奖学金、德国亚历山大洪堡奖学金、吉林省三八红旗手、全国五一巾帼标兵等奖项和荣誉称号。现任《高等学校化学学报》第一届青年执行编委。

代表性成果

代表论文:

1. Wenyao Zhen, Yang Liu, Wei Wang, Mengchao Zhang, Wenxue Hu, Xiaodan Jia, Chao Wang, and Xiue Jiang*. Specific “unlocking” of a nanozyme-based butterfly effect to break the evolutionary fitness of chaotic tumors. Angewandte Chemie-International Edition, 2020, 59(24), 9491-9497.

2. Shanshan Li, Lie Wu, Xiaofei Zhang, and Xiue Jiang*. The structure of water bonded to phosphate groups at the electrified zwitterionic phospholipid membranes/aqueous interface. Angewandte Chemie-International Edition, 2020, 59(16), 6627-6630.

3. Wenyao Zhen, Yang Liu, Mengchao Zhang, Wenxue Hu, Wei Wang, Xiaodan Jia,, and Xiue Jiang*. Multi-caged IrOx for facile preparation of “six-in-one” nanoagent for subcutaneous and lymphatic tumors inhibition against recurrence and metastasis. Advanced Functional Materials, 2020, 30(24), 2002274.

4. Chao Wang, Fengjuan Cao, Yudi Ruan, Xiaodan Jia, Wenyao Zhen, and Xiue Jiang*. Specific generation of singlet oxygen through the russell mechanism in hypoxic tumors and GSH depletion by Cu-TCPP nanosheets for cancer therapy. Angewandte Chemie-International Edition, 2019, 58(29), 9846-9850.

5. Jing Bai, Xiaodan Jia, Wenyao Zhen, Wenlong Cheng* and Xiue Jiang*. A facile ion-doping strategy to regulate tumor microenvironments for enhanced multimodal tumor theranostics. Journal of the American Chemical Society, 2018, 140(1): 106-109.

6. Wenyao Zhen, Yang Liu, Lin Lin, Jing Bai, Xiaodan Jia, Huayu Tian*, and Xiue Jiang*. BSA-IrO2: catalase-like nanoparticles with high photothermal conversion efficiency and a high X-ray absorption coefficient for anti-inflammation and antitumor theranostics. Angewandte Chemie-International Edition, 2018, 57(32): 10309-10313

7. Zhifang Ma, Xiaodan Jia, Jing Bai, Yudi Ruan, Chao Wang, Jianming Li, Mengchao Zhang*, and Xiue Jiang*. MnO2 gatekeeper: an intelligent and O2-evolving shell for preventing premature release of high cargo payload core, overcoming tumor hypoxia, and acidic H2O2-sensitive MRI. Advanced Functional Materials, 2017, 27(4): 1604258.

8. Lie Wu, Li Zeng, and Xiue Jiang*. Revealing the nature of interaction between graphene oxide and lipid membrane by surface-enhanced infrared absorption spectroscopy. Journal of the American Chemical Society, 2015, 137(32): 10052-10055.

9. Xiue Jiang, Martin Engelhard, Kenichi Ataka*, and Joachim Heberle. Molecular impact of the membrane potential on the regulatory mechanism of proton transfer in sensory rhodopsin II. Journal of the American Chemical Society, 2010, 132(31): 10808-10815.

10. Xiue Jiang#, Ekaterina Zaitseva#, Michael Schmidt, Friedrich Siebert, Martin Engelhard, Ramona Schlesinger, Kenichi Ataka, Reiner Vogel*, and Joachim Heberle*. Resolving voltage-dependent structural changes of a membrane photoreceptor by surface-enhanced IR difference spectroscopy. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2008, 105(34): 12113-1211.

代表专利:

  1. 发明专利:一种红外光谱仪反射附件

  专利号:ZL 201210101360.1

  发明(设计)人:姜秀娥 安宅慧一 白静

  授权公告日:2014-03-12

  2. 发明专利:一种提高表面增强红外吸收光谱的增强因子的方法

  专利号:ZL 201210418056.X

  发明(设计)人:曹凤娟 姜秀娥

  授权公告日:2016-03-23

  3. 发明专利:一种Bi2Te3二维纳米片、其制备方法及应用

  专利号:ZL 201510454096.3

  发明(设计)人:姜秀娥 白静 贾潇丹

  授权公告日:2017-11-28

  4. 发明专利:一种C3N4纳米复合材料、制备方法及其应用

  专利号:ZL 201510979958.4

  发明(设计)人:姜秀娥 马志方 白静 贾潇丹

  授权公告日:2018-10-16

代表著作:

  1. Xiue Jiang, Jing Bai, Tiantian Wang, Basicas for the preparation of quantum dots and their interactions with living cells, Quantum dots: applications in biology》, Humana Press, 2014, New York. (专著章节)

  2. Lie Wu, Xiue Jiang, Infrared Spectroscopy for Studying Plasma Membranes, Membrane BiophysicsNew Insights and Methods》,Springer, 2018, Singapore. (专著章节)

重大成果: